Increase transduction efficiency with receptor boosters

Transduction of hMSCs with adenovirus. Human mesenchymal stem cells (hMSCs) that are normally resistant to transduction by adenovirus vectors are rendered susceptible by treatment with the CAR Receptor Booster. hMSCs were plated in 6-well plates 24 hr prior to transduction. CAR Receptor Booster (20 µl) was added, and the cells were incubated for 2 hr at 37°C followed by addition of Adeno-X ZsGreen1 virus (MOI~190). Cells were assayed for fluorescence activity 24 hr post transduction.

Cat. # Product Package Size Price
631470 CAR Receptor Booster 20 Rxns $245.00
632269 Adeno-X™ Adenoviral System 3 (CMV) 10 Rxns $1092.00

Curious about other innovative adenovirus-related products from Clontech?

Check out our Adeno-X GoStix™, Tetracycline-Inducible System, Titration Kits and Purification Kits.

Receptor Boosters prime target cells for infection by temporarily elevating the density of cell-surface viral receptor proteins. The CAR Receptor Booster, for example, allows you to efficiently transduce cells that are normally resistant to adenoviral infection, such as hematopoietic cells or CHO cells. In fact, the technology allows you to increase the infection efficiency of any cell type that is resistant to transduction by adenovirus. More product information >>

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